Tadalafil (Generic Cialis) Online Prescription

Written and clinically reviewed by Bidwell Cranage, APRN, FNP-C · Published April 18, 2026
Last clinically reviewed:
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Tadalafil, the active ingredient in Cialis, can be prescribed for erectile dysfunction as a daily or as-needed regimen. Bidwell Health offers a $45 online assessment in Florida and 10 other states. Tell your clinician how often you expect to use treatment and whether you have tried ED medication before. If appropriate, your prescription goes to your chosen pharmacy. The visit has no required subscription; medication and any shipping cost extra.

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Quick facts
Generic name
tadalafil
Brand names
Cialis, Adcirca
Drug class
PDE5 inhibitor
RxCUI
358263
Treats
ED, BPH, BPH + ED (also: pulmonary arterial hypertension as Adcirca)
Common doses
2.5 mg or 5 mg daily; 5 mg, 10 mg or 20 mg as needed
Typical start
2.5 mg daily or 10 mg as needed; individualized by the prescriber
Onset
30-45 minutes (PRN)
Duration
Up to 36 hours per dose
Half-life
~17.5 hours
Pharmacy cost
Varies by pharmacy, quantity, insurance, and discount-card pricing
Controlled?
No; prescription only

Can I get generic Cialis online in Florida?

Eligible adult men physically located in Florida can request tadalafil through a $45 Bidwell ED visit. You can state a preference for daily or as-needed use, but a Florida-licensed clinician chooses the appropriate medication, dose and quantity.

Use our Florida online ED treatment service for generic Cialis and other options to review the visit pathway. Living in Florida does not establish eligibility while you are visiting a state we do not serve; your physical location at the time of care matters. Read the step-by-step Florida ED prescription guide if you want to understand the process before submitting an intake.

What is tadalafil?

Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor, the same drug class as sildenafil, vardenafil, and avanafil. All PDE5 inhibitors work by preserving cyclic GMP in the smooth muscle of the corpus cavernosum, allowing blood to fill the penis during sexual arousal. What makes tadalafil distinctive is its 17.5-hour half-life; far longer than sildenafil's 4 hours; which gives a clinical window of up to 36 hours per dose. The Cialis prescribing information is the authoritative reference.

Cialis is the brand name; tadalafil is the active ingredient. An FDA-approved generic must meet the same standards for strength, quality and clinical benefit. Tadalafil also has an approved use for BPH, but this page and the linked intake concern ED assessment. Urinary symptoms alone need their own evaluation rather than being assumed to be an ED visit.

Who qualifies for tadalafil through Bidwell

Tadalafil is an appropriate first-line treatment for most adult men with ED, per the American Urological Association guideline. You can request an assessment through Bidwell if you:

Tadalafil is often a better fit than sildenafil if you want a longer window, prefer daily dosing without planning, or also have BPH symptoms. It's less affected by food so you don't need an empty stomach.

When tadalafil may be unsafe

Do not take tadalafil with nitrates, nitrites or riociguat.

This includes nitroglycerin, isosorbide and recreational "poppers." The combination can dangerously lower blood pressure. Do not use tadalafil if you have had an allergic reaction to it or an ingredient in the tablet.

Tell your clinician about recent heart or stroke events, blood-pressure problems, severe liver or kidney disease, dialysis, a history of sudden vision loss or retinal disease, or prolonged erections. These can require a different dose, a different treatment or an in-person assessment. ED medication should not be used when sexual activity is unsafe because of your heart condition.

Alpha-blockers and other medicines can change the risk. Your clinician reviews the combination and dose; spacing tablets does not remove an interaction. See the MedlinePlus patient guide for precautions. If chest pain develops, seek emergency care and tell the team when you last took tadalafil; do not self-administer a nitrate.

How to get tadalafil online through Bidwell

1
Start the ED intake. At bidwellhealth.com/start-visit. About 3 minutes. Your history, medications, cardiovascular status, and preferences for daily vs PRN dosing.
2
Review the $45 visit fee and submit. This covers clinician assessment with no required subscription or video visit. Medication is separate. If the clinician determines online care is not appropriate, your visit fee is refunded. A prescription is not guaranteed.
3
Licensed U.S. clinician reviews. Your intake is reviewed 7 days a week, including weekends.
4
Choose where to fill an approved prescription. Your prescription can go to any licensed local or mail-order pharmacy that can fill it, including Amazon Pharmacy or Cost Plus Drugs. Your pharmacy handles pickup or delivery and charges separately for medication and shipping.

Typical tadalafil dosing

RegimenDoseWhen to use
Daily (low-dose)2.5 mg daily, adjusted to 5 mg when appropriateA regular daily schedule rather than a tablet timed to each occasion
As needed (PRN)10 mg initially; adjusted to 5 mg or 20 mg when appropriateInfrequent use; take 30-45 min before. Max once per 24 hours.

For as-needed dosing, take tadalafil 30-45 minutes before anticipated activity. Unlike sildenafil, food doesn't meaningfully affect absorption; you can take it with or without a meal. Do not exceed the prescribed frequency. Kidney disease or interacting medicines can require a lower dose or an interval longer than 24 hours.

Daily dosing provides steady-state PDE5 inhibition. Most men on daily tadalafil find they don't need to "plan" around doses; if sex happens, the medication is already working. Daily dosing is also the only FDA-approved PDE5 regimen for BPH. The AUA BPH guideline includes tadalafil 5 mg daily as a first-line option, especially for men with both BPH and ED.

Dosing caveat: Your prescribing provider chooses the dose based on your age, kidney and liver function, other medications, and goals. These are general ranges from the FDA label.

Common side effects

Tadalafil is generally well tolerated. Per the FDA label, the most common side effects are:

Serious but rare side effects: priapism (erection lasting more than 4 hours; medical emergency, go to the ER), sudden hearing loss, NAION (rare form of vision loss), severe allergic reactions. Stop the medication and seek urgent care for sudden vision or hearing changes.

Back pain and muscle aches are more associated with tadalafil than sildenafil, typically starting 12-24 hours after dosing and resolving on their own or with acetaminophen/ibuprofen. If persistent or severe, consider switching agents. For more detail, see our tadalafil side effects guide and the sildenafil vs tadalafil comparison.

Common drug interactions

What will daily or as-needed tadalafil cost?

Bidwell charges $45 for the assessment, with tadalafil and shipping paid separately. The visit includes 21 days of messaging about the same visit. The visit process guide explains when that window starts; your portal shows its end date. There is no required subscription or video appointment.

A daily prescription and an as-needed prescription have different quantities. The intake offers 30, 60 or 90 tablets for daily tadalafil, or 15, 30 or 45 tablets for as-needed use. Your clinician decides the dose and final quantity and may authorize one refill. Once the approved supply and refill are used, another prescription needs a new $45 visit.

Pharmacy example, checked September 28, 2026: Cost Plus Drugs lists 30 tadalafil 5 mg tablets for $5.97, plus $5.25 standard shipping. With a $45 Bidwell visit, that example totals $56.22 before tax for the visit and one fill. Your clinician selects the dose; confirm the current price for your prescribed strength and quantity with your pharmacy.

For other strengths, quantities and regimens, see our ED cost comparison for daily and as-needed medication. Compare the visit fee, tablet count, refill allowance and delivery charges together.

Bidwell does not bill insurance for the visit. Ask your chosen pharmacy whether insurance or a cash discount gives the better medication price.

Available in 11 states

FloridaVirginiaWashington ArizonaColoradoConnecticutIowa MarylandMontanaNew MexicoUtah

You must be physically located in one of these states at the time of your visit.

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Frequently asked questions

Can I get generic Cialis online in Florida?

Yes. Eligible adult men physically in Florida can request a $45 Bidwell ED assessment. A licensed clinician decides whether tadalafil is appropriate, and an approved prescription goes to the patient's chosen pharmacy. Medication and shipping are separate. See online ED treatment in Florida for the care pathway.

Can I get tadalafil prescribed online?

Yes. Eligible adults in Florida and the other supported states can request an online ED assessment for $45. A licensed clinician decides whether tadalafil is appropriate and can send an approved prescription to your chosen pharmacy. The visit has no required subscription or video appointment; medication is separate.

How is tadalafil different from sildenafil?

Main difference: duration. Sildenafil lasts 4-6 hours; tadalafil lasts up to 36. Tadalafil can be taken daily for continuous coverage (2.5 or 5 mg) and is FDA-approved for BPH. Sildenafil is shorter-acting and a bit more affected by food.

What's the difference between daily and PRN tadalafil?

Daily tadalafil is prescribed as 2.5 mg or 5 mg taken on a regular schedule. As-needed, or PRN, tadalafil is taken before anticipated sexual activity, with 5 mg, 10 mg or 20 mg selected by the clinician. Do not add an as-needed dose to a daily regimen unless your prescriber specifically instructs you.

How much does generic tadalafil cost?

Medication cost is paid separately at the pharmacy and varies by strength, quantity, pharmacy, insurance, and discount-card pricing. Generic tadalafil is usually less expensive than brand-name Cialis.

Does tadalafil really last 36 hours?

As-needed tadalafil can improve erectile response for up to 36 hours after a dose. That is a window of possible response, not a continuous erection or a guaranteed duration. Sexual stimulation is still needed. An erection lasting more than four hours needs emergency care.

Can tadalafil help with enlarged prostate?

Tadalafil 5 mg daily has an FDA-approved use for benign prostatic hyperplasia, or BPH. However, the Bidwell intake linked here is for ED. New urinary symptoms need clinical evaluation; do not use an ED visit as a substitute for assessing their cause.

Can I drink alcohol with tadalafil?

Alcohol can add to tadalafil's blood-pressure effects, particularly in larger amounts, and can worsen erectile difficulty. Discuss your alcohol use with the clinician. Seek advice for dizziness or fainting rather than assuming a fixed number of drinks is safe.

Is generic tadalafil the same as Cialis?

FDA-approved generic tadalafil has the same active ingredient as Cialis and must meet FDA standards for equivalent clinical benefit at the corresponding strength. Inactive ingredients and appearance can differ. This guide covers FDA-approved generic tadalafil tablets.

Can I switch between sildenafil and tadalafil?

A clinician can help you switch if the duration, side effects or dosing routine do not fit your needs. Do not overlap sildenafil and tadalafil or choose your own switching interval; ask your prescriber when to stop one and start the other.

Can I take tadalafil with food?

Yes. Unlike sildenafil, food doesn't meaningfully delay absorption. You can take it with or without a meal.

Related reading

Sources

Sources checked September 28, 2026.

Clinically reviewed by Bidwell Cranage, APRN, FNP-C, AANP board-certified Family Nurse Practitioner, licensed in 11 states.
Last reviewed: